Article
E3 ubiquitin ligase Pub1 is implicated in endocytosis of a GPI-anchored protein Ecm33 in fission yeast.
PloS one - 1 Jan 2014
Fang Yue, Jaiseng Wurentuya, Ma Yan, Hu Lingling, Yamazaki Shizuka, Zhang Xibo, Hayafuji Tsutomu, Shi Lin, Kuno Takayoshi
Abstract excerpt
We previously identified three glycosylphosphatidylinositol (GPI)-anchored proteins including Ecm33, as multicopy suppressors of the phenotypes of a mutant allele of cis4(+) that encodes a zinc transporter in fission yeast. Here, we further identified two multicopy suppressor genes, ubi1 (+) and ubc4 (+), encoding ubiquitin-ribosomal fusion protein and ubiquitin conjugating enzyme E2, respectively. In addition,...
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