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Mapping the single-cell landscape of acral melanoma and analysis of the molecular regulatory network of the tumor microenvironments

27 Jul 2022

Abstract excerpt

Acral melanoma (AM) exhibits a high incidence in Asian patients with melanoma, and it is not well treated with immunotherapy. However, little attention has been paid to the characteristics of the immune microenvironment in AM. Therefore, in this study, we collected clinical samples from Chinese patients with AM and conducted single-cell RNA sequencing to analyze the heterogeneity of its tumor microenvironments...

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PMID: 35894206
DOI: 10.7554/elife.78616

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