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Association of IDH1 Mutation and MGMT Promoter Methylation with Clinicopathological Parameters in an Ethnically Diverse Population of Adults with Gliomas in England

29 Nov 2024

Abstract excerpt

Background: Molecular profiles can predict which patients will respond to current standard treatment and new targeted therapy regimens. Using data from a highly diverse population of approximately three million in Southeast London and Kent, this study aims to evaluate the prevalence of IDH1 mutation and MGMT promoter methylation in the gliomas diagnosed in adult patients and to explore correlations with patients’...

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Share to Epigenetics and DNA Methylation
Share to Glioma Diagnosis and Treatment
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PMID: 39767640
DOI: 10.3390/biomedicines12122732

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