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High Prevalence of Hepatitis B Virus Drug Resistance Mutations to Lamivudine among People with HIV/HBV Coinfection in Rural and Peri-Urban Communities in Botswana.

Viruses - 11 Apr 2024

Phinius Bonolo B, Anderson Motswedi, Gobe Irene, Mokomane Margaret, Choga Wonderful T, Phakedi Basetsana, Ratsoma Tsholofelo, Mpebe Gorata, Makhema Joseph, Shapiro Roger, Lockman Shahin, Musonda Rosemary, Moyo Sikhulile, Gaseitsiwe Simani

Abstract excerpt

(1) Background: We aimed to determine the prevalence of hepatitis B virus (HBV) resistance-associated mutations (RAMs) in people with HBV and human immunodeficiency virus (HBV/HIV) in Botswana. (2) Methods: We sequenced HBV deoxyribonucleic acid (DNA) from participants with HBV/HIV from the Botswana Combination Prevention Project study (2013-2018) using the Oxford Nanopore GridION platform. Consensus sequences...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38675933
DOI: 10.3390/v16040592
PMCID: PMC11054684

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