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Article

Viral load suppression and HIV-1 drug resistance mutations in persons with HIV on TLD/TAFED in Zambia.

PloS one - 1 Jan 2024

Luwaya Emmanuel L, Mwape Lackson, Bwalya Kaole, Siakabanze Chileleko, Hamooya Benson M, Masenga Sepiso K

Abstract excerpt

BACKGROUND: An increase in the prevalence of HIV drug resistance (HIVDR) has been reported in recent years, especially in persons on non-nucleoside reverse transcriptase inhibitors (NNRTIs) due to their low genetic barrier to mutations. However, there is a paucity of epidemiological data quantifying HIVDR in the era of new drugs like dolutegravir (DTG) in sub-Saharan Africa. We, therefore, sought to determine the...

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PMID: 39241081
DOI: 10.1371/journal.pone.0308869
PMCID: PMC11379217

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