Article
Clonal Hematopoiesis of Indeterminate Potential in Crohn’s Disease and Ulcerative Colitis
6 Jan 2025
Abstract excerpt
BACKGROUND: Clonal hematopoiesis of indeterminate potential (CHIP) is the presence of somatic mutations in myeloid and lymphoid malignancy genes in the blood cells of individuals without a hematologic malignancy. Inflammation is hypothesized to be a key mediator in the progression of CHIP to hematologic malignancy and patients with CHIP have a high prevalence of inflammatory diseases. This study aimed to identify...
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