Article
Causal relationship between inflammatory cytokines, metabolites, and ulcers of lower limb: A Mendelian randomization study.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society - 1 Jan 2000
Mo Yongjun, Zhou Peilin, Wang Wenqiang, Liu Yongzhen, Lin Zhanming, Dong Shunan, Wei Lu, Nie Xinyu, Hua Qikai
Abstract excerpt
Inflammatory cytokines are key indicators affecting the development of ulcers of lower limb. The causal role of inflammatory cytokines in ulcers of lower limb and whether this can be mediated by metabolites remain unknown. We conducted a two-step, two-sample Mendelian randomization (MR) study to investigate the causal effect of inflammatory cytokines on ulcers of lower limb and the mediating role of metabolites...
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