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Evolution of the SARS-CoV-2 Omicron spike

18 Nov 2023

Abstract excerpt

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern, first identified in November 2021, rapidly spread worldwide and diversified into several subvariants. The Omicron spike (S) protein accumulated an unprecedented number of sequence changes relative to previous variants. In this review, we discuss how Omicron S protein structural features modulate host cell receptor...

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PMID: 37979169
DOI: 10.1016/j.celrep.2023.113444

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