Characterizing features affecting local ancestry inference performance in admixed populations.

Abstract excerpt

In recent years, significant efforts have been made to improve methods for genomic studies of admixed populations using local ancestry inference (LAI). Accurate LAI is crucial to ensure that downstream analyses accurately reflect the genetic ancestry of research participants. Here, we test analytic strategies for LAI to provide guidelines for optimal accuracy, focusing on admixed populations reflective of Latin...

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• American Indian or Alaska Native
• Black People
• Genetics, Population
• Genome, Human
• Latin America