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Article

Recomb-Mix: fast and accurate local ancestry inference.

Bioinformatics (Oxford, England) - 1 Jul 2025

Wei Yuan, Zhi Degui, Zhang Shaojie

Abstract excerpt

MOTIVATION: The availability of large genotyped cohorts brings new opportunities for revealing the high-resolution genetic structure of admixed populations via local ancestry inference (LAI), the process of identifying the ancestry of each segment of an individual haplotype. Though current methods achieve high accuracy in standard cases, LAI is still challenging when reference populations are more similar (e.g....

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Topics

Humans
Haplotypes
Software
Genetics, Population
Algorithms
Polymorphism, Single Nucleotide
Genotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Models, Genetic

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Identifiers

PMID: 40662780
DOI: 10.1093/bioinformatics/btaf227
PMCID: PMC12261469

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