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Developmental heterogeneity of embryonic neuroendocrine chromaffin cells and their maturation dynamics

27 Sept 2022

Abstract excerpt

During embryonic development, nerve-associated Schwann cell precursors (SCPs) give rise to chromaffin cells of the adrenal gland via the “bridge” transient stage, according to recent functional experiments and single cell data from humans and mice. However, currently existing data do not resolve the finest heterogeneity of developing chromaffin populations. Here we took advantage of deep SmartSeq2 transcriptomic...

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PMID: 36237181
DOI: 10.3389/fendo.2022.1020000

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