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Article

Sexual Dimorphism in the Expression of Mitochondria-Related Genes in Rat Heart at Different Ages

23 Jan 2015

Abstract excerpt

Cardiovascular disease (CVD) is the leading cause of mortality worldwide. Moreover, sex and age are considered major risk factors in the development of CVDs. Mitochondria are vital for normal cardiac function, and regulation of mitochondrial structure and function may impact susceptibility to CVD. To identify potential role of mitochondria in sex-related differences in susceptibility to CVD, we analyzed the basal...

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PMID: 25615628
DOI: 10.1371/journal.pone.0117047

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