Article
Abnormalities in rich-club connections are associated with an exacerbation of genetic susceptibility to schizophrenia.
BMC psychiatry - 27 Dec 2024
Li Yang, Sun Eryi, Dai Rao, Chen Jian, Huang Haixia, Shan Xiuhong, Li Yuefeng
Abstract excerpt
BACKGROUND: Schizophrenia (SZ) is a highly heritable and heterogeneous disorder that is often associated with widespread structural brain abnormalities. However, the causes of interindividual differences in genetic susceptibility remain largely unknown. This study attempted to address this important issue by utilizing a prospective study in which unaffected first-degree relatives of SZ (FH+) were recruited....
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