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Extensive methylation analysis of circulating tumor DNA in plasma of patients with gastric cancer

27 Dec 2024

Abstract excerpt

DNA methylation is known to be involved in tumor progression. This is the first study to perform an extensive methylation analysis of plasma circulating tumor DNA (ctDNA) using targeted bisulfite sequencing in gastric cancer (GC) patients to evaluate the usefulness of ctDNA methylation as a new biomarker. Sixteen patients who received chemotherapy for recurrent GC were included. After confirmation of the...

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PMID: 39730450
DOI: 10.1038/s41598-024-79252-y

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