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Article

[High expression of AURKB promotes malignant phenotype of osteosarcoma cells by activating nuclear factor-κB signaling via DHX9].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 20 Dec 2024

Zhong Yanxin, Liu Yu, Tong Weilai, Xie Xinsheng, Nie Jiangbo, Yang Feng, Liu Zhili, Liu Jiaming

Abstract excerpt

OBJECTIVES: To investigate the regulatory mechanism of aurora kinase B (AURKB) for promoting malignant phenotype of osteosarcoma cells. METHODS: HA-Vector or HA-AURKB was transfected in 293T cells to identify the molecules interacting with AURKB using immunoprecipitation combined with liquid chromatography-tandem mass spectrometry followed by verification with co-immunoprecipitation and Western blotting. In...

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Identifiers

PMID: 39725619
DOI: 10.12122/j.issn.1673-4254.2024.12.06
PMCID: PMC11683349

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