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Decoding cancer etiology with cellular reprogramming.

Current opinion in genetics & development - 1 Feb 2025

Huang Mo-Fan, Fisher Megan E, Phan Trinh T T, Zhao Ruiying, Lee Dung-Fang

Abstract excerpt

Cancer research remains clinically unmet in many areas due to limited access to patient samples and the lack of reliable model systems that truly reflect human cancer biology. The emergence of patient-derived induced pluripotent stem cells and engineered human pluripotent stem cells (hPSCs) has helped overcome these challenges, offering a versatile alternative platform for advancing cancer research. These hPSCs...

Topics

Humans
Cellular Reprogramming
Neoplasms
Induced Pluripotent Stem Cells
Mutation
Pluripotent Stem Cells

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39721322
DOI: 10.1016/j.gde.2024.102301
PMCID: PMC11830421

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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