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Article

Linking Pluripotency Reprogramming and Cancer.

Stem cells translational medicine - 1 Feb 2017

Iglesias Juan Manuel, Gumuzio Juan, Martin Angel G

Abstract excerpt

Tumor development and the generation of induced pluripotent stem cells are highly comparable processes with striking similarities. Cellular plasticity is inherent to tumor evolution, rendering cells that acquire a stem cell-like phenotype, for which Sox2 activation has proved instrumental for the plastic acquisition of stemness properties in tumor cells. Understanding the molecular mechanisms underlying both...

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Share to Cell Movement
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Induced Pluripotent Stem Cells

Share to Neoplasm Invasiveness

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Share to SOXB1 Transcription Factors

Source

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Identifiers

PMID: 28191771
DOI: 10.5966/sctm.2015-0225
PMCID: PMC5442824

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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