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Article

Polygenic prediction of occupational status GWAS elucidates genetic and environmental interplay in intergenerational transmission, careers and health in UK Biobank.

Nature human behaviour - 1 Feb 2025

Akimova Evelina T, Wolfram Tobias, Ding Xuejie, Tropf Felix C, Mills Melinda C

Abstract excerpt

Socioeconomic status (SES) impacts health and life-course outcomes. This genome-wide association study (GWAS) of sociologically informed occupational status measures (ISEI, SIOPS, CAMSIS) using the UK Biobank (N = 273,157) identified 106 independent single-nucleotide polymorphisms of which 8 are novel to the study of SES. Genetic correlations with educational attainment (rg = 0.96-0.97) and income...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39715877
DOI: 10.1038/s41562-024-02076-3
PMCID: PMC11860221

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