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Article

Genome-wide association study of occupational attainment as a proxy for cognitive reserve.

Brain : a journal of neurology - 24 May 2022

Ko Hyunwoong, Kim Soyeon, Kim Kiwon, Jung Sang-Hyuk, Shim Injeong, Cha Soojin, Lee Hyewon, Kim Beomsu, Yoon Joohyun, Ha Tae Hyon, Kwak Seyul, Kang Jae Myeong, Lee Jun-Young, Kim Jinho, Park Woong-Yang, Nho Kwangsik, Kim Doh Kwan, Myung Woojae, Won Hong-Hee

Abstract excerpt

Occupational attainment, which represents middle-age cognitive activities, is a known proxy marker of cognitive reserve for Alzheimer's disease. Previous genome-wide association studies have identified numerous genetic variants and revealed the genetic architecture of educational attainment, another marker of cognitive reserve. However, the genetic architecture and heritability for occupational attainment remain...

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Identifiers

PMID: 34613391
DOI: 10.1093/brain/awab351

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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