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Article

Hereditary spastic paraplegias: When to expect bladder dysfunction a genetic and urodynamic study.

European journal of neurology - 1 Jan 2025

Lallemant-Dudek Pauline, Guillaud-Bataille Marine, Hentzen Claire, Joussain Charles, Pichon Bertrand, Robain Gilberte, Haddad Rebecca, Coarelli Giulia, Heinzmann Anna, Denys Pierre, Amarenco Gérard, Durr Alexandra

Abstract excerpt

BACKGROUND: The aim of this study was to characterize hereditary spastic paraplegias (HSP) patients' urodynamic profiles and development of bladder symptoms. METHODS: This is a multicentric retrospective study which included patients presenting with bladder disorders. We reviewed medical and urodynamic records in individuals with HSP and recorded age at onset of gait and bladder disorders, disability stage at the...

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Age of Onset
Aged
SPAST gene
SPG11 gene
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Spastic Paraplegia, Hereditary

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Open in PubMed Open full text

Identifiers

PMID: 39704400
DOI: 10.1111/ene.70003
PMCID: PMC11660083

Genes

SPAST
SPG11
SPG7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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