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Article

The prevalence of hereditary spastic paraplegia and the occurrence of SPG4 mutations in Estonia.

Neuroepidemiology - 1 Jan 2009

Braschinsky Mark, Luus Siiri-Merike, Gross-Paju Katrin, Haldre Sulev

Abstract excerpt

BACKGROUND: Hereditary spastic paraplegia (HSP) is a clinically and genetically heterogeneous disorder, with a variable reported prevalence ranging from 0.5 to 12 per 100,000. The aim of this retrospective study was to evaluate the prevalence of HSP and estimate the percentage of SPG4 mutations in the Estonian population. METHODS: A simple model with multiple data sources was selected to enable as many patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19039240
DOI: 10.1159/000177033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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