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Article

Mendelian randomization studies in ankylosing spondylitis: A systematic review.

International journal of rheumatic diseases - 1 Nov 2024

Wei Jiangnan, Zhu Xiuyuan, Wang Jiaxian, Yang Kezhou, Chen Jiayin, Li Jingling, Zuo Shunli, Liu Ning

Abstract excerpt

INTRODUCTION: Previous research has revealed connections between ankylosing spondylitis (AS) and comorbid conditions. However, observational studies frequently encounter difficulties in establishing definitive causal links between potential risk factors and AS. In contrast, Mendelian randomization (MR) offers a more robust approach to exploring causality by leveraging the random allocation of alleles at birth,...

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Comorbidity
Gastrointestinal Microbiome
Genetic Predisposition to Disease
Inflammatory Bowel Diseases
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Spondylitis, Ankylosing

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PMID: 39503365
DOI: 10.1111/1756-185X.15408

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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