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Article

Causal relationship between the immune cells and ankylosing spondylitis: univariable, bidirectional, and multivariable Mendelian randomization.

Frontiers in immunology - 1 Jan 2024

Qin Chaofan, Yu Qingshuai, Deng Zhongliang, Zhang You, Chen Mingxin, Wang Xin, Hu Tao, Lei Bo, Yan Zhengjian, Cheng Si

Abstract excerpt

Background: Ankylosing spondylitis (AS) is an autoimmune disease that affects millions of individuals. Immune cells have been recognized as having a crucial role in the pathogenesis of AS. However, their relationship has not been fully explored. Methods: We chose to employ Mendelian randomization (MR) to investigate the potential correlation between immune cells and AS. We sourced the data on immune cells from...

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CD4 gene
Genetic Predisposition to Disease
Genome-Wide Association Study
Mendelian Randomization Analysis
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Spondylitis, Ankylosing

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PMID: 38655262
DOI: 10.3389/fimmu.2024.1345416
PMCID: PMC11035830

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CD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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