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Article

Proteomic and metabolomic exploration in relapse acute myeloid leukemia bone marrow supernatant combined with genetic characteristics.

BMC cancer - 18 Dec 2024

Ji Xinyao, Yang Cheng, Niu Changchun

Abstract excerpt

OBJECT: Aim to investigate the multi-omic characteristics of the bone marrow supernatant of relapsed acute myeloid leukemia (AML) and search for proteins and metabolites associated with relapse. METHODS: A total of 40 bone marrow supernatant from 7 patients with relapsed AML and 33 patients with non-relapsed AML were collected for proteomics and metabonomics analysis. Unsupervised clustering was used to discover...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39695514
DOI: 10.1186/s12885-024-13286-3
PMCID: PMC11657831

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