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Mutational landscape of plasma cell-free DNA identifies molecular features associated with therapeutic response in patients with colon cancer. A pilot study.

Mutagenesis - 6 Oct 2021

Cervena Klara, Pardini Barbara, Urbanova Marketa, Vodenkova Sona, Eva Pazourkova, Veskrnova Veronika, Levy Miroslav, Buchler Tomas, Mokrejs Martin, Naccarati Alessio, Vodicka Pavel, Vymetalkova Veronika

Abstract excerpt

Cell-free DNA (cfDNA) has recently been used as a non-invasive diagnostic tool for detecting tumour-specific mutations. cfDNA may also be used for monitoring disease progression and treatment response, but so far researchers focused on one or few genes only. A genomic profile may provide better information on patient prognosis compared to single specific mutations. In this hypothesis-generating study, we profiled...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34214148
DOI: 10.1093/mutage/geab024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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