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Article

The AGT epistasis pattern proposed a novel role for ZBED9 in regulating blood pressure: Tehran Cardiometabolic genetic study (TCGS).

Gene - 15 Jul 2022

Akbarzadeh Mahdi, Riahi Parisa, Kolifarhood Goodarz, Lanjanian Hossein, Alipour Nadia, Najd Hassan Bonab Leila, Reza Moghadas Mohammad, Sabour Siamak, Azizi Fereidoun, Daneshpour Maryam S

Abstract excerpt

INTRODUCTION: High blood pressure is widely regarded as the most important risk factor for cardiovascular diseases. Epistasis analysis may provide additional insight into the genetic basis of hypertension. METHODS: A nested case-control design was used on 4214 unrelated Tehran Cardiometabolic Genetic Study (TCGS) adults to evaluate 65 SNPs of previously associated genes, including ZBED9, AGT, and TNXB. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35577038
DOI: 10.1016/j.gene.2022.146560

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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