Parkinson's disease: what the model systems have taught us so far.

Abstract excerpt

Parkinson's disease (PD) is a debilitating neurodegenerative disorder, for which people above the age of 60 show an increased risk. Although there has been great advancement in understanding the disease-related abnormalities in brain circuitry and development of symptomatic treatments, a cure for PD remains elusive. The discovery of PD associated gene mutations and environmental toxins have yielded animal models...

Topics

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• Disease Models, Animal
• Gene-Environment Interaction
• Inflammation
• Models, Biological
• Mutation