Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Developing a Novel and Optimized Yeast Model for Human VDAC Research.

International journal of molecular sciences - 3 Dec 2024

Baranek-Grabińska Martyna, Grabiński Wojciech, Musso Deborah, Karachitos Andonis, Kmita Hanna

Abstract excerpt

The voltage-dependent anion-selective channel (VDAC) plays a crucial role in mitochondrial function, and VDAC paralogs are considered to ensure the differential integration of mitochondrial functions with cellular activities. Heterologous expression of VDAC paralogs in the yeast Saccharomyces cerevisiae por1Δ mutant cells is often employed in studies of functional differentiation of human VDAC paralogs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mitochondria
Share to Mutation
Share to Saccharomyces cerevisiae

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Saccharomyces cerevisiae Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 39684721
DOI: 10.3390/ijms252313010
PMCID: PMC11641349

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Developing a Novel and Optimized Yeast Model for Human VDAC Research.PMID 39684721Read ↗

Overexpression of human SOD1 in VDAC1-less yeast restores mitochondrial functionality modulating beta-barrel outer membrane protein genes.Semantic proximity Read ↗

Role of cysteines in mammalian VDAC isoforms' function.Semantic proximity Read ↗

Multicopy suppressors of phenotypes resulting from the absence of yeast VDAC encode a VDAC-like protein.Semantic proximity Read ↗

Targeting Copper Homeostasis Improves Functioning of vps13Δ Yeast Mutant Cells, a Model of VPS13-Related Diseases.Semantic proximity Read ↗

Human NKCC2 cation–Cl– co-transporter complements lack of Vhc1 transporter in yeast vacuolar membranes.Semantic proximity Read ↗

In Vivo Characterization of I91T Sod2 Polymorphism of Saccharomyces cerevisiae.Semantic proximity Read ↗

Mutation in the peroxin-coding gene PEX22 contributing to high malate production in Saccharomyces cerevisiae.Semantic proximity Read ↗

Cd2+, Mn2+, Ni2+ and Se2+ toxicity to Saccharomyces cerevisiae lacking YPK9p the orthologue of human ATP13A2Semantic proximity Read ↗

Sym1, the yeast ortholog of the MPV17 human disease protein, is a stress-induced bioenergetic and morphogenetic mitochondrial modulator.Semantic proximity Read ↗

Channeling studies in yeast: yeast as a model for channelopathies?Semantic proximity Read ↗

Exploring Yeast as a Study Model of Pantothenate Kinase-Associated Neurodegeneration and for the Identification of Therapeutic Compounds.Semantic proximity Read ↗

Three mitochondrial transporters of Saccharomyces cerevisiae are essential for ammonium fixation and lysine biosynthesis in synthetic minimal medium.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.