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Article

In Vivo Characterization of I91T Sod2 Polymorphism of Saccharomyces cerevisiae.

Journal of cellular biochemistry - 1 May 2017

de Carvalho Mariana Dias Castela, De Mesquita Joelma Freire, Eleutherio Elis Cristina Araujo

Abstract excerpt

The mitochondrial antioxidant enzyme Mn-Superoxide Dismutase (Sod2) is essential for mammalian survival. I82T mutation in human Sod2 has been linked to a wide variety of diseases, including Alzheimer's and Parkinson's diseases as well as some types of cancers. Yeast wild-type (WT) Sod2 and the mutant Sod2 I91T, which corresponds to the human mutant Sod2 I82T, were cloned in sod2Δ strain. Residue I82 is conserved...

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PMID: 27584980
DOI: 10.1002/jcb.25720

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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