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Article

Targeting Copper Homeostasis Improves Functioning of vps13Δ Yeast Mutant Cells, a Model of VPS13-Related Diseases.

International journal of molecular sciences - 24 Feb 2021

Soczewka Piotr, Tribouillard-Tanvier Déborah, di Rago Jean-Paul, Zoladek Teresa, Kaminska Joanna

Abstract excerpt

Ion homeostasis is crucial for organism functioning, and its alterations may cause diseases. For example, copper insufficiency and overload are associated with Menkes and Wilson's diseases, respectively, and iron imbalance is observed in Parkinson's and Alzheimer's diseases. To better understand human diseases, Saccharomyces cerevisiae yeast are used as a model organism. In our studies, we used the vps13Δ yeast...

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PMID: 33668157
DOI: 10.3390/ijms22052248
PMCID: PMC7956333

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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