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Article

Molecular Genetic Profile of 300 Japanese Patients with Diffuse Gliomas Using a Glioma-tailored Gene Panel.

Neurologia medico-chirurgica - 15 Sept 2022

Higa Nayuta, Akahane Toshiaki, Yokoyama Seiya, Yonezawa Hajime, Uchida Hiroyuki, Fujio Shingo, Kirishima Mari, Takigawa Kosuke, Hata Nobuhiro, Toh Keita, Yamamoto Junkoh, Hanaya Ryosuke, Tanimoto Akihide, Yoshimoto Koji

Abstract excerpt

Rapid technological advances in molecular biology, including next-generation sequencing, have identified key genetic alterations in central nervous system (CNS) tumors. Accordingly, the fifth edition of the World Health Organization (WHO) CNS tumor classification was published in 2021. We analyzed 303 patients with diffuse glioma using an amplicon-based glioma-tailored gene panel for detecting 1p/19q codeletion...

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Astrocytoma
Brain Neoplasms
Genetic Profile
Glioma
Isocitrate Dehydrogenase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Biology

Sequence Deletion

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Identifiers

PMID: 36031351
DOI: 10.2176/jns-nmc.2022-0103
PMCID: PMC9534570

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