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Article

Coding Variants in HOOK2 and GTPBP3 May Contribute to Risk of Primary Angle Closure Glaucoma.

DNA and cell biology - 1 Jun 2020

Qiao Chunyan, Jia Hongyan, Zhang Hui, Wang Hui, Liang Jing, Song Jing, Li Liang, Duan Xiaoming, Cao Kai, Hu Jianping

Abstract excerpt

Primary angle closure glaucoma (PACG) is a major cause of blindness worldwide. This study proposed to screen candidate PACG-associated variants in Chinese Han people. Whole exome sequencing was applied to five confirmed PACG patients and two primary angle closure suspect individuals within a PACG-enriched Chinese Han family. A series of bioinformatics analyses were implemented to obtain high-risk single...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32397755
DOI: 10.1089/dna.2019.5079

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