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Article

Genetically Determined Plasma Docosahexaenoic Acid Showed a Causal Association with Female Reproductive Longevity-Related Phenotype: A Mendelian Randomization Study.

Nutrients - 28 Nov 2024

Gao Huajing, Ying Yuewen, Sun Jing, Huang Yun, Li Xue, Zhang Dan

Abstract excerpt

BACKGROUND: Female reproductive aging remains irreversible. More evidence is needed on how polyunsaturated fatty acids (PUFAs) affect the female reproductive lifespan. OBJECTIVES: To identify and validate specific PUFAs that can influence the timing of menarche and menopause in women. METHODS: We utilized a two-sample Mendelian randomization (MR) framework to evaluate the causal relationships between various...

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Identifiers

PMID: 39683497
DOI: 10.3390/nu16234103
PMCID: PMC11643456

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