Exploring the Causal Effects of Physical Activity, Sedentary Behaviour, and Diet on Atrial Fibrillation and Heart Failure: A Multivariable Mendelian Randomisation Analysis

Abstract excerpt

AIMS: This study aimed to investigate the causal effects of physical activity, sedentary behaviour, and diet on atrial fibrillation (AF) and heart failure (HF) using multivariate Mendelian randomization (MR) analysis and genetic variants as instrumental variables. METHODS: The study employed multivariate MR analysis with physical activity, sedentary behaviour, and diet as exposures and AF and HF as outcomes. Data...

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• Cardiovascular Effects of Exercise
• Genetic Associations and Epidemiology
• Genetics and Physical Performance