Article
Exome Sequencing Identified Susceptible Genes for High Residual Risks in Early-Onset Coronary Atherosclerotic Disease.
Clinical cardiology - 1 Dec 2024
Wu Runda, Su Ya, Liao Jianquan, Shen Juan, Ma Yuanji, Gao Wei, Dong Zheng, Dai Yuxiang, Yao Kang, Ge Junbo
Abstract excerpt
AIMS: Despite the tremendous improvement in therapeutic medication and intervention for coronary atherosclerotic disease (CAD), residual risks remain. Exome sequencing enables identification of rare variants and susceptibility genes for residual risks of early-onset coronary atherosclerotic disease (EOCAD) with well-controlled conventional risk factors. METHODS: We performed whole-exome sequencing of subjects who...
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