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Article

Whole Exome Sequencing to Identify Genetic Variants Associated with Raised Atherosclerotic Lesions in Young Persons.

Scientific reports - 22 Jun 2017

Hixson James E, Jun Goo, Shimmin Lawrence C, Wang Yizhi, Yu Guoqiang, Mao Chunhong, Warren Andrew S, Howard Timothy D, Heide Richard S Vander, Van Eyk Jennifer, Wang Yue, Herrington David M

Abstract excerpt

We investigated the influence of genetic variants on atherosclerosis using whole exome sequencing in cases and controls from the autopsy study "Pathobiological Determinants of Atherosclerosis in Youth (PDAY)". We identified a PDAY case group with the highest total amounts of raised lesions (n = 359) for comparisons with a control group with no detectable raised lesions (n = 626). In addition to the standard exome...

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Source

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Identifiers

PMID: 28642624
DOI: 10.1038/s41598-017-04433-x
PMCID: PMC5481334

Genes

CAD
MAF
NBEAL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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