Developing, Characterizing, and Modeling CRISPR-Based Point-of-Use Pathogen Diagnostics

Abstract excerpt

Recent years have seen intense interest in the development of point-of-care nucleic acid diagnostic technologies to address the scaling limitations of laboratory-based approaches. Chief among these are combinations of isothermal amplification approaches with CRISPR-based detection and readouts of target products. Here, we contribute to the growing body of rapid, programmable point-of-care pathogen tests by...

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