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The neonatal Fc receptor (FcRn) is required for porcine reproductive and respiratory syndrome virus uncoating

9 Dec 2024

Abstract excerpt

ABSTRACT Porcine reproductive and respiratory syndrome virus (PRRSV) continues to cause substantial economic losses to the pig industry worldwide. Previous studies from other groups showed that CD163 is required for PRRSV uncoating and genome release. However, CD163 does not interact with nucleocapsid (N) protein. In this study, the neonatal Fc receptor (FcRn) was demonstrated to be irreplaceable for PRRSV...

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PMID: 39651859
DOI: 10.1128/jvi.01218-24

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