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Article

Revisiting mutational resistance to ampicillin and cefotaxime in Haemophilus influenzae.

Genome medicine - 4 Dec 2024

Diricks Margo, Petersen Sabine, Bartels Lennart, Lâm Thiên-Trí, Claus Heike, Bajanca-Lavado Maria Paula, Hauswaldt Susanne, Stolze Ricardo, Vázquez Omar Jiménez, Utpatel Christian, Niemann Stefan, Rupp Jan, Wohlers Inken, Merker Matthias

Abstract excerpt

BACKGROUND: Haemophilus influenzae is an opportunistic bacterial pathogen that can cause severe respiratory tract and invasive infections. The emergence of β-lactamase-negative ampicillin-resistant (BLNAR) strains and unclear correlations between genotypic (i.e., gBLNAR) and phenotypic resistance are challenging empirical treatments and patient management. Thus, we sought to revisit molecular resistance...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39633433
DOI: 10.1186/s13073-024-01406-4
PMCID: PMC11616347

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