Article
Diversity of beta-lactam resistance-conferring amino acid substitutions in penicillin-binding protein 3 of Haemophilus influenzae.
Antimicrobial agents and chemotherapy - 1 Jul 2002
Dabernat Henri, Delmas Catherine, Seguy Martine, Pelissier Roseline, Faucon Genevieve, Bennamani Safia, Pasquier Christophe
Abstract excerpt
The sequences of the ftsI gene, encoding the transpeptidase domain of penicillin binding protein (PBP) 3A and/or PBP 3B, which are involved in septal peptidoglycan synthesis, were determined for 108 clinical strains of Haemophilus influenzae with reduced susceptibility to beta-lactam antibiotics with or without beta-lactamase production and were compared to those of the ampicillin-susceptible Rd strain and...
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