Article
Single nucleotide polymorphisms in genes encoding penicillin-binding proteins in β-lactamase-negative ampicillin-resistant Haemophilus influenzae in Japan.
BMC research notes - 20 Jan 2018
Misawa Kazuhisa, Tarumoto Norihito, Tamura Shinsuke, Osa Morichika, Hamamoto Takaaki, Yuki Atsushi, Kouzaki Yuji, Imai Kazuo, Ronald Runtuwene Lucky, Yamaguchi Toshiyuki, Murakami Takashi, Maesaki Shigefumi, Suzuki Yutaka, Kawana Akihiko, Maeda Takuya
Abstract excerpt
OBJECTIVE: β-Lactamase-negative ampicillin-resistant Haemophilus influenzae is a common opportunistic pathogen of hospital- and community-acquired infections, harboring multiple single nucleotide polymorphisms in the ftsI gene, which codes for penicillin-binding protein-3. The objectives of this study were to perform comprehensive genetic analyses of whole regions of the penicillin-binding proteins in H....
Topics
- Ampicillin
- Ampicillin Resistance
- Anti-Bacterial Agents
- Bacterial Proteins
- Genotype
- Haemophilus Infections
- Haemophilus influenzae
- Humans
- Microbial Sensitivity Tests