Article
Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime.
Antimicrobial agents and chemotherapy - 1 Jul 2007
García-Cobos Silvia, Campos José, Lázaro Edurne, Román Federico, Cercenado Emilia, García-Rey César, Pérez-Vázquez María, Oteo Jesús, de Abajo Francisco
Abstract excerpt
The sequence of the ftsI gene encoding the transpeptidase domain of penicillin-binding protein 3 (PBP 3) was determined for 354 nonconsecutive Haemophilus influenzae isolates from Spain; 17.8% of them were ampicillin susceptible, 56% were beta-lactamase nonproducing ampicillin resistant (BLNAR), 15.8% were beta-lactamase producers and ampicillin resistant, and 10.4% displayed both resistance mechanisms. The ftsI...
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