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Article

Decoding the genome of SARS-CoV-2: a pathway to drug development through translation inhibition

4 Dec 2024

Abstract excerpt

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the coronavirus disease 2019 (COVID-19) pandemic and is continuously spreading globally. The continuous emergence of new SARS-CoV-2 variants keeps posing threats, highlighting the need for fast-acting, mutation-resistant broad-spectrum therapeutics. Protein translation is vital for SARS-CoV-2 replication, producing early non-structural...

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PMID: 39630134
DOI: 10.1080/15476286.2024.2433830

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