Article
HLA-G 3' UTR-2 haplotype is associated with Human African trypanosomiasis susceptibility.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2013
Courtin David, Milet Jacqueline, Sabbagh Audrey, Massaro Juliana D, Castelli Erick C, Jamonneau Vincent, Bucheton Bruno, Sese Claude, Favier Benoit, Rouas-Freiss Nathalie, Moreau Philippe, Donadi Eduardo A, Garcia André
Abstract excerpt
Trypanosoma brucei gambiense (Tbg) is responsible for the chronic form of Human African trypanosomiasis (HAT), classically lasting for years. Clinical evolution of HAT cases seems to be complex and reports on asymptomatic carriers and spontaneous cure have been published recently, strengthening the likely existence of the phenomenon of human trypanotolerance. Host's genetic factors could be involved in both the...
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