Identification of neural alterations in patients with Crohn’s disease with a novel multiparametric brain MRI-based radiomics model

Abstract excerpt

OBJECTIVES: Gut-brain axis dysfunction has emerged as a key contributor to the pathogenesis of Crohn's disease (CD). The elucidation of neural alterations may provide novel insights into its management. We aimed to develop a multiparameter brain MRI-based radiomics model (RM) for characterizing neural alterations in CD patients and to interpret these alterations using multiomics traits. METHODS: This prospective...

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