Article

A distinct serum metabolic signature outperforms C-reactive protein as a non-invasive marker for monitoring disease activity in Inflammatory Bowel Disease

2025-12-11

Abstract excerpt

<h4>Background</h4> Achieving deep remission, such as e.g. histo-endoscopic remission, is a key objective in inflammatory bowel disease (IBD). However, this metric depends on invasive procedures that are impractical in routine care, whereas current non-invasive blood biomarkers demonstrate only limited correlation with disease activity. <h4>Objective</h4> We used serum metabolomics to identify blood-based signat...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7d53dd3e-acdb-5edd-901c-dffe55493e55
DOI: 10.64898/2025.12.10.25341951

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A distinct serum metabolic signature outperforms C-reactive protein as a non-invasive marker for monitoring disease activity in Inflammatory Bowel DiseaseDOI 10.64898/2025.12.10.25341951Read

Identifying Robust Biomarkers for the Diagnosis and Subtype Distinction of Inflammatory Bowel Disease through Comprehensive Serum Metabolomic ProfilingSemantic proximity Read

Identifying robust biomarkers for the diagnosis and subtype distinction of inflammatory bowel disease through comprehensive serum metabolomic profilingSemantic proximity Read

Exploring the utility of metabolic profiling in stratifying patient groups in Inflammatory Bowel DiseaseSemantic proximity Read

Serum Metabolomics Identifies Altered Bioenergetics, Signaling Cascades in Parallel with Exposome Markers in Crohn’s DiseaseSemantic proximity Read

IBD metabonomics predicts phenotype, disease course, and treatment response.Semantic proximity Read

Multi-omics phenotyping characterizes molecular divergence underlying different clinical scenarios of inflammatory bowel diseaseSemantic proximity Read

Deciphering the microbiome–metabolome landscape of an inflammatory bowel disease inception cohortSemantic proximity Read

The faecal metabolome and its determinants in inflammatory bowel diseaseSemantic proximity Read

Proteomics and metabolomics in inflammatory bowel disease.Semantic proximity Read

Systematic Mining of gut microbiota biomarkers for IBDSemantic proximity Read

Targeted 1H NMR metabolomics and immunological phenotyping of human fresh blood and serum samples discriminate between healthy individuals and inflammatory bowel disease patients treated with anti-TNF.Semantic proximity Read

Multi-omics empowered deep phenotyping of ulcerative colitisSemantic proximity Read