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Association Between Circulating Vitamin K Levels, Gut Microbiome, and Type 1 Diabetes: A Mendelian Randomization Study.

Nutrients - 5 Nov 2024

De La Barrera Samuel, De La Barrera Benjamin, Legault Marc-André, Gamache Isabel, Manousaki Despoina

Abstract excerpt

BACKGROUND/OBJECTIVES: Nutritional deficiencies have been proposed as possible etiological causes for autoimmune diseases, among which type 1 diabetes (T1D). Vitamin K (VK) has potentially positive effects on type 2 diabetes, but its role on T1D in humans remains largely unknown. We aimed to examine the presence of a causal association between VK and T1D using a Mendelian randomization (MR) approach. METHODS:...

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Share to Diabetes Mellitus, Type 1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39599583
DOI: 10.3390/nu16223795
PMCID: PMC11597649

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