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Article

Associations between vitamin D and autoimmune diseases: Mendelian randomization analysis.

Seminars in arthritis and rheumatism - 1 Oct 2023

Zhao Sizheng Steven, Mason Amy, Gjekmarkaj Eva, Yanaoka Haruyuki, Burgess Stephen

Abstract excerpt

OBJECTIVE: The VITAL trial of vitamin D supplementation suggested a possible protective effect for autoimmune diseases but uncertainties remain. We investigated potential causal effects of vitamin D on composite and individual autoimmune diseases using Mendelian randomization. METHODS: We used data from 332,984 participants of the UK Biobank of whom 23,089 had at least one autoimmune disease defined using ICD...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37437450
DOI: 10.1016/j.semarthrit.2023.152238
PMCID: PMC7614794

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