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Mendelian randomization study of inflammatory bowel disease and type 1 diabetes.

Endocrine - 1 Dec 2024

Zhu Jing-Yi, Ma Xinyi, Liu Mu-Yun, Ma Li-Zhe, Sun Xiao-Ru, Yan Mao-Yun, Xue Chunyu, Sun Chang

Abstract excerpt

PURPOSE: Our purpose was to investigate and test the causal relationship between type 1 diabetes (T1D) and inflammatory bowel disease (IBD) and its major phenotypes, including ulcerative colitis (UC) and Crohn's disease (CD), in two large datasets. METHODS: We obtained IBD samples from the largest publicly available genome-wide association study (GWAS), as well as the FinnGen database and the publicly accessible...

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Colitis, Ulcerative
Crohn Disease
Diabetes Mellitus, Type 1
Genetic Predisposition to Disease
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Inflammatory Bowel Diseases

Mendelian Randomization Analysis

Polymorphism, Single Nucleotide

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PMID: 39083171
DOI: 10.1007/s12020-024-03919-9

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