Article
Vitamin D levels and risk of type 1 diabetes: A Mendelian randomization study.
PLoS medicine - 1 Feb 2021
Manousaki Despoina, Harroud Adil, Mitchell Ruth E, Ross Stephanie, Forgetta Vince, Timpson Nicholas J, Smith George Davey, Polychronakos Constantin, Richards J Brent
Abstract excerpt
BACKGROUND: Vitamin D deficiency has been associated with type 1 diabetes in observational studies, but evidence from randomized controlled trials (RCTs) is lacking. The aim of this study was to test whether genetically decreased vitamin D levels are causally associated with type 1 diabetes using Mendelian randomization (MR). METHODS AND FINDINGS: For our two-sample MR study, we selected as instruments single...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.